CMD – Liza Pon, Ph.D.

CMD - Liza Pon, Ph.D.
Liza Pon was inspired to study CHKB congenital muscular dystrophy by her first encounter with a patient, who helped her see the impact the disease has on patients and their families and understand the urgent need to develop therapies.

Liza Pon, professor of pathology and cell biology at Columbia University in New York was awarded an MDA research grant totaling $300,000 over three years to study the underlying mechanisms at work in CHKB congenital muscular dystrophy (CMD). Pon also will test whether therapies that promote function of a protein known as the ryanodine receptor (RyR), which plays a critical role in contraction of skeletal and heart muscle, can promote muscle function or prevent muscle degeneration in a mouse model for CHKB CMD and in muscle cells taken from CHKB CMD patients.

Funding for this MDA research grant began Aug. 1, 2015.