Muscle disease – Colin Crist, Ph.D.

Muscle disease - Colin Crist, Ph.D.
Applications of Colin Crist’s research include development of stem cell based treatments and discovery of modifiers of muscle stem cell activity within the body as novel therapeutic targets for the treatment of muscular dystrophy.

Colin Crist, an assistant professor in the department of human genetics at McGill University in Québec, Canada, was awarded an MDA research grant totaling $300,000 over three years to investigate a biological mechanism that determines whether skeletal muscle stem cells, which play an important role in muscle regeneration, self-renew or differentiate. Crist has identified inhibitors that control this functional “switch.” This work may inform muscular dystrophy therapy development.

Funding for this MDA research grant began Aug. 1, 2015.