Researchers are looking for people to participate in a clinical trial, sponsored by Cedars-Sinai Medical Center, to test the safety and efficacy of beetroot juice extract in people with Becker muscular dystrophy (BMD).

Beetroot juice is rich in molecules called nitrates, which are converted to nitric oxide in the body. Study researchers will assess whether increased levels of nitric oxide produced in the body after consuming beet root juice extract cause an increase in blood flow to muscle.

In the Phase 1 open label study, called “Skeletal Muscle Blood Flow in Becker Muscular Dystrophy,” all participants will receive treatment with beetroot juice orally or via intravenous injection. Study investigators will assess whether the drug has positive effects on blood flow and handgrip strength.

Participants will be asked to make up to three clinic visits. Medical tests performed during each visit may include contrast enhanced ultrasound, EKG, and handgrip testing. Throughout the study, participants will continue to see their regular doctor for routine care.

People ages 18-60 years, with a diagnosis of BMD and who meet additional criteria may be eligible to participate.

This study is recruiting at Cedars-Sinai Medical Center in Los Angeles. Travel and hotel accommodations may be provided for those who must travel to the test site for clinic visits.

For additional information on travel and accommodations, or to learn more or to inquire about participation, contact Matthew Hakimi, M.D., at 310-248-8080. You can also find out more information on the study by visiting ClinicalTrials.gov and searching for NCT02653833.