Research Study Alert: Natural History Study in Males with BMD

Researchers at the University of Florida are seeking adult males living with Becker muscular dystrophy (BMD) to participate in a three-year natural history study. The objective of this observational study is to gain a better understanding of the course of BMD and to identify biomarkers for BMD.

This study does not involve an intervention. Enrolled participants will be required to complete three doctor visits over the course of the three-year study (ie. One visit per year). During these visits, participants will be evaluated using tests such as magnetic resonance imaging (MRI), magnetic resonance spectroscopy (MRS), and a number of functional tests. For ambulatory participants, the 6 minute walk test, 10 meter walk/run, North Star Ambulatory Assessment, and timed functional measures may be performed. All participants may be tested using Performance of Upper Limb test, Pulmonary Function Test, a blood sample, a urine sample, and a one-time needle biopsy of two leg muscles.

To be eligible, individuals must meet the following inclusion criteria:

  • Ambulatory or non-ambulatory male
  • Between the ages of 18-62
  • Diagnosis of BMD

Individuals may not be eligible to participate if they meet the following exclusion criteria:

  • Internal pace maker or internal cardio-defibrillator
  • Dependent on daytime mechanical ventilation and/or medically unstable
  • Secondary condition that may impact muscle function
  • Any contradiction to MRI  

Please visit this link for the full listing of inclusion and exclusion criteria.

To inquire about participation, contact the Study Coordinator Claudia Senesac by telephone: (352) 273-6453 or email csenesac@phhp.ufl.edu.